Industrial Fermentation-Grade Bone Peptone – High-Performance Nitrogen Source for Optimal Microbial Growth

Product Description:

Sichuan Shihong Technology Co., Ltd. presents Industrial Fermentation-Grade Bone Peptone, a specialized protein hydrolysate engineered to maximize microbial growth and metabolic activity in large-scale fermentation processes. Produced through controlled enzymatic digestion of premium cattle bones, this advanced nutrient substrate delivers exceptional nitrogen bioavailability, making it an indispensable component for industrial biotechnology applications where yield, consistency, and process efficiency are critical.

Fermentation-Specific Advantages:

• Enhanced Microbial Metabolism: With total nitrogen ≥14.5% and amino nitrogen ≥2.5%, our peptone provides readily assimilable nitrogen compounds that stimulate rapid cell proliferation and optimize metabolite production in aerobic/anaerobic fermentations.

• Process-Stable Formulation: Maintains consistent pH (5–7) and resists precipitation even under high-temperature sterilization (121°C/20min), ensuring reliable performance throughout extended fermentation cycles.

• Low Interference Profile: Minimal inorganic content (NaCl ≤5.0%, ash ≤5.0%) reduces the risk of ionic imbalance in sensitive fermentation media, particularly crucial for recombinant protein expression and antibiotic production.

• Batch-to-Batch Consistency: Rigorous quality control guarantees uniform amino acid profiles and solubility characteristics, eliminating variability in industrial-scale fermentation outcomes.

Technical Specifications for Fermentation Optimization:

Targeted Fermentation Applications:

• Antibiotic Production: Serves as core nitrogen source in penicillin, streptomycin, and cephalosporin fermentations, demonstrating superior performance versus plant-based peptones.

• Amino Acid Synthesis: Optimized for L-lysine, glutamic acid, and tryptophan production through tailored amino acid release during fermentation.

• Yeast & Bacterial Biomass: Ideal for baker's yeast, probiotic cultures, and single-cell protein cultivation due to balanced peptide chain lengths.

• Industrial Enzyme Fermentation: Enhances cellulase, amylase, and protease yields through sustained nitrogen release matching microbial growth phases.

Fermentation Process Support:

• Pre-Fermentation Testing: Available upon request to validate performance with specific strains and bioreactor configurations.

• Custom Hydrolysis Profiles: Adjustable peptide chain length distributions to match uptake kinetics of proprietary production strains.

Quality Assurance for Fermentation Integrity:
Every batch undergoes:

1. Bioreactor Simulation Testing to confirm growth promotion characteristics

2. Heavy Metal Screening (Pb <0.5ppm, As <0.3ppm) for sensitive GMP applications

3. Endotoxin Control (<50EU/g) for pharmaceutical-grade fermentations

Packaging for Industrial Use:

• 20kg multi-barrier bags with moisture and oxygen barriers

• Palletized shipments available for bulk fermentation facilities

Technical Partnership Program:
Collaborate with our fermentation specialists to:

• Develop strain-specific nutrient formulations

• Optimize nitrogen feeding strategies for fed-batch systems

• Troubleshoot media-related yield limitations